Pathogenesis of infections related to intravascular catheterization.

Update on pathogenesis and diagnosis of intravascular catheter-related infections.

Infections associated with the use of intravascular catheters cause a substantial morbidity and mortality. New knowledge in the pathogenesis of catheter related bloodstream infections has led to advances in the prevention and management of these infections. The purpose of the present chapter is to review the most relevant data published recently on pathogenesis and diagnosis of intravascular ca...

Prevention of intravascular catheter-related infections.

PURPOSE To review the literature on prevention of intravascular catheter-related infections. DATA SOURCES The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. Primary authors were contacted directly if data were incomplete. STUDY SELECTION Studies met the following criteria unless otherwise stated: Trials ...

Management of intravascular catheter-related infections.

Prevention of intravascular catheter-related bloodstream infections.

solution available in clinical settings, especially when current Centers for Disease Control and Prevention guidelines state that only solutions of PPD containing 5 TU/0.1 mL should be used.1 We have discontinued the 250 TU formulation in our institution. We urge caution in the interpretation of tuberculin tests and suggest careful examination of the strength of the solution before administration.

New technologies to prevent intravascular catheter-related bloodstream infections.

Most intravascular catheter-related infections are associated with central venous catheters. Technologic advances shown to reduce the risk for these infections include a catheter hub containing an iodinated alcohol solution, short-term chlorhexidine-silver sulfadiazine- impregnated catheters, minocycline-rifampin-impregnated catheters, and chlorhexidine- impregnated sponge dressings. Nontechnol...